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Early experiences. Genetic modifications that respond to hormones in the womb may explain the development of homosexuality. From a strictly Darwinian viewpoint, homosexuality shouldn't still be around. It isn't the best way to pass along one's genes, and to complicate the picture further, no "gay genes" have even been identified. According to a newly released hypothesis, the explanation may not lie in DNA itself. Instead, as an embryo develops, sex-related genes are turned on and off in response to fluctuating levels of hormones in the womb, produced by both mother and child.
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A Genetic Study of Male Sexual Orientation

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Arch Gen Psychiatry. These studies used either convenience samples, most without controls, or population-based samples in which confounding factors such as depression and substance abuse were not measured. An analytic sample of middle-aged male-male twin pairs from the registry was identified in which one member of the pair reported male sex partners after age 18 years while the other did not. Four lifetime symptoms of suicidality as measured by the Diagnostic Interview Schedule were analyzed: thoughts about death, wanting to die, thoughts about committing suicide, and attempted suicide.
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Homosexuality May Start in the Womb

Sexual orientation of relatives was assessed either by asking relatives directly, or when this was impossible, asking the probands. Heritabilities were substantial under a wide range of assumptions about the population base rate of homosexuality and ascertainment bias. However, the rate of homosexuality among nontwin biological siblings, as reported by probands, 9. A proband's self-reported history of childhood gender nonconformity did not predict homosexuality in relatives in any of the three subsamples.
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The relationship between the environment and sexual orientation is a subject of research. In the study of sexual orientation , some researchers distinguish environmental influences from hormonal influences, [1] while other researchers include biological influences such as prenatal hormones as part of environmental influences. Scientists do not know the exact cause of sexual orientation, but they theorize that it is the result of a complex interplay of genetic , hormonal , and environmental influences. Hypotheses for the impact of the post-natal social environment on sexual orientation are weak, especially for males. Often, sexual orientation and sexual orientation identity are not distinguished, which can impact accurately assessing sexual identity and whether or not sexual orientation is able to change; sexual orientation identity can change throughout an individual's life, and may or may not align with biological sex, sexual behavior or actual sexual orientation.
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